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1

Apoptotic program is initiated but not completed in LNCaP cells in response to growth in charcoal-stripped media

Saeed, Badr, Zhang, Haichao, Ng, Shi-Chung

Journal:

Year:

1997

Language:

english

File:

PDF, 440 KB

english, 1997

2

10.1038/44617

Fesik, Stephen W., Sun, Chaohong, Cai, Mengli, Gunasekera, Angelo H., Meadows, Robert P., Wang, Hong, Chen, Jun, Zhang, Haichao, Wu, Wei, Xu, Nan, Ng, Shi-Chung

Journal:

Year:

1999

Language:

english

File:

PDF, 405 KB

english, 1999

3

MIM capacitor integration for mixed-signal/RF applications

Chit Hwei Ng, Chaw-Sing Ho, Shao-Fu Sanford Chu, Shi-Chung Sun

Journal:

IEEE Transactions on Electron Devices

Year:

2005

Language:

english

File:

PDF, 764 KB

english, 2005

4

Induction of apoptosis in prostatic tumor cell line DU145 by staurosporine, a potent inhibitor of protein kinases

Zhang, Haichao, Hoang, Thuc, Saeed, Badr, Ng, Shi-Chung

Journal:

Year:

1996

Language:

english

File:

PDF, 721 KB

english, 1996

5

Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms

Jie Qian, Martin J Voorbach, Jeffrey R Huth, Michael L Coen, Haichao Zhang, Shi-Chung Ng, Kenneth M Comess, Andrew M Petros, Saul H Rosenberg, Usha Warrior, David J Burns

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 512 KB

english, 2004

6

Development of a high-throughput robotic fluorescence-based assay for HsEg5 inhibitor screening

Bin Zhang, David Senator, Christopher J. Wilson, Shi-Chung Ng

Journal:

Analytical Biochemistry

Year:

2005

Language:

english

File:

PDF, 326 KB

english, 2005

7

Indoloprodigiosins from the C-10 bipyrrolic precursor: New antiproliferative prodigiosin analogs

Carmen M. Baldino, Jonathan Parr, Christopher J. Wilson, Shi-Chung Ng, Daniel Yohannes, Harry H. Wasserman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 148 KB

english, 2006

8

Privileged structure-based quinazolinone natural product-templated libraries: Identification of novel tubulin polymerization inhibitors

Ji-Feng Liu, Christopher J. Wilson, Ping Ye, Kevin Sprague, Katie Sargent, Ying Si, Galina Beletsky, Daniel Yohannes, Shi-Chung Ng

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 159 KB

english, 2006

9

Development of a high-throughput fluorescence polarization assay for Bcl-xL

Haichao Zhang, Paul Nimmer, Saul H Rosenberg, Shi-Chung Ng, Mary Joseph

Journal:

Analytical Biochemistry

Year:

2002

Language:

english

File:

PDF, 208 KB

english, 2002

10

Novel sulfonate Derivatives: potent antimitotic agents

Stephen L. Gwaltney II, Hovis M. Imade, Qun Li, Laura Gehrke, R.Bruce Credo, Robert B. Warner, Jang Yun Lee, Peter Kovar, David Frost, Shi-Chung Ng, Hing L. Sham

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 138 KB

english, 2001

11

Potent inhibitors of protein farnesyltransferase: Heteroarenes as cysteine replacements

Wang Shen, Stephen Fakhoury, Greg Donner, Kenneth Henry, Jang Lee, Haichao Zhang, Jerry Cohen, Robert Warner, Badr Saeed, Sajeev Cherian, Stephen Tahir, Peter Kovar, Joy Bauch, Shi-Chung Ng, Kennan Ma

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 319 KB

english, 1999

12

Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients

Phillip Kim, Xinjun Liu, Tani Lee, Limin Liu, Robert Barham, Richard Kirkland, Glen Leesman, Anne Kuller, Belen Ybarrondo, Shi-Chung Ng, Sharat Singh

Journal:

Proteome Science

Year:

2011

Language:

english

File:

PDF, 583 KB

english, 2011

13

Aliphatic1H and13C resonance assignments for the 26-10 antibody VLdomain derived from heteronuclear multidimensional NMR spectroscopy

Keith L. Constantine, Valentina Goldfarb, Michael Wittekind, Mark S. Friedrichs, James Anthony, Shi-Chung Ng, Luciano Mueller

Journal:

Journal of Biomolecular NMR

Year:

1993

Language:

english

File:

PDF, 913 KB

english, 1993

14

Cloning and Characterization of the Rat Gene Encoding GAP-43

Ed Grabczyk, Mauricio X. Zuber, Howard J. Federoff, Shi-Chung Ng, Alison Pack, Mark C. Fishman

Journal:

European Journal of Neuroscience

Year:

1990

Language:

english

File:

PDF, 932 KB

english, 1990

15

10.1038/31972

Fesik, Stephen W., Eberstadt, Matthias, Huang, Baohua, Chen, Zehan, Meadows, Robert P., Ng, Shi-Chung, Zheng, Lixin, Lenardo, Michael J.

Journal:

Year:

1998

Language:

english

File:

PDF, 879 KB

english, 1998

16

Efficient Production of a Functional Single-Chain Antidigoxin Antibody via an Engineered Bacillus subtilis Expression-Secretion System

Wu, Xu-Chu, Ng, Shi-Chung, Near, Richard I., Wong, Sui-Lam

Journal:

Year:

1993

File:

PDF, 872 KB

1993

17

Divergence of Genbank and human tumor Bcl-2 sequences and implications for binding affinity to key apoptotic proteins

Joseph, Mary K, Solomon, Larry R, Petros, Andrew M, Cai, Jill, Simmer, Robert L, Zhang, Haichao, Rosenberg, Saul, Ng, Shi-Chung

Journal:

Year:

2004

Language:

english

File:

PDF, 187 KB

english, 2004

18

Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL

Oost, Thorsten K., Belli, Barbara A., Ding, Hong, Bruncko, Milan, Joseph, Mary K., Kunzer, Aaron, Martineau, Darlene, McClellan, William J., Mitten, Michael, Ng, Shi-Chung

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 755 KB

english, 2007

19

Novel One-Pot Total Syntheses of Deoxyvasicinone, Mackinazolinone, Isaindigotone, and Their Derivatives Promoted by Microwave Irradiation

Liu, Ji-Feng, Ye, Ping, Sprague, Kevin, Sargent, Katie, Yohannes, Daniel, Baldino, Carmen M., Wilson, Christopher J., Ng, Shi-Chung

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 95 KB

english, 2005

20

Disulfide bonds protect the encapsidated chromosomes of simian virus 40

Shi-Chung Ng, Minou Bina

Journal:

Year:

1981

Language:

english

File:

PDF, 455 KB

english, 1981

21

Crystal structure of HsEg5 in complex with clinical candidate CK0238273 provides insight into inhibitory mechanism, potency, and specificity

Bin Zhang, Ji-Feng Liu, Yingwu Xu, Shi-Chung Ng

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 1.56 MB

english, 2008

22

Potent Farnesyltransferase Inhibitor ABT-100 Abrogates Acute Allograft Rejection

Ming-Sing Si, Ping Ji, Michael Lee, Jennifer Kwok, Jamie Kusumoto, Eric Naasz, Shi-Chung Ng, David K. Imagawa

Journal:

The Journal of Heart and Lung Transplantation

Year:

2005

Language:

english

File:

PDF, 221 KB

english, 2005

23

Crystal Structure and Mutagenic Analysis of the Inhibitor-of-Apoptosis Protein Survivin

Steven W. Muchmore, Jun Chen, Clarissa Jakob, Dorothy Zakula, Edmund D. Matayoshi, Wei Wu, Haichao Zhang, Fengzhi Li, Shi-Chung Ng, Dario C. Altieri

Journal:

Year:

2000

Language:

english

File:

PDF, 627 KB

english, 2000

24

Farnesyltransferase inhibition: a novel method of immunomodulation

Ming-Sing Si, Ping Ji, Bruce J. Tromberg, Mike Lee, Jennifer Kwok, Shi-Chung Ng, David K. Imagawa

Journal:

International Immunopharmacology

Year:

2003

Language:

english

File:

PDF, 221 KB

english, 2003

25

Production of stable anti-digoxin Fv in escherichia coli

James Anthony, Richard Near, Wong Sui-lam, Eric Iida, Eileen Ernst, Michael Wittekind, Edgar Haber, Ng Shi-Chung

Journal:

Molecular Immunology

Year:

1992

Language:

english

File:

PDF, 2.17 MB

english, 1992

26

GAP-43 gene expression during development: persistence in a distinctive set of neurons in the mature central nervous system

Suzanne M. De la Monte, Howard J. Federoff, Shi-Chung Ng, Ed Grabczyk, Mark C. Fishman

Journal:

Developmental Brain Research

Year:

1989

Language:

english

File:

PDF, 3.07 MB

english, 1989

27

Design and Synthesis of a Quinazolinone Natural Product-Templated Library with Cytotoxic Activity

Liu, Ji-Feng, Kaselj, Mira, Isome, Yuko, Ye, Ping, Sargent, Katie, Sprague, Kevin, Cherrak, Djamel, Wilson, Christopher J., Si, Ying, Yohannes, Daniel, Ng, Shi-Chung

Journal:

Journal of Combinatorial Chemistry

Year:

2006

Language:

english

File:

PDF, 108 KB

english, 2006

28

Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo

Wendt, Michael D., Shen, Wang, Kunzer, Aaron, McClellan, William J., Bruncko, Milan, Oost, Thorsten K., Ding, Hong, Joseph, Mary K., Zhang, Haichao, Nimmer, Paul M., Ng, Shi-Chung, Shoemaker, Alexande

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 343 KB

english, 2006

29

Downregulation of Akt1 Inhibits Anchorage-Independent Cell Growth and Induces Apoptosis in Cancer Cells

Liu, Xuesong, Shi, Yan, Han, Edward K.-H., Chen, Zehan, Rosenberg, Saul H., Giranda, Vincent L., Luo, Yan, Ng, Shi-Chung

Journal:

Year:

2001

Language:

english

File:

PDF, 299 KB

english, 2001

30

Blocking CHK1 Expression Induces Apoptosis and Abrogates the G2 Checkpoint Mechanism

Luo, Yan, Rockow-Magnone, Shayna K., Kroeger, Paul E., Frost, Leigh, Chen, Zehan, Han, Edward K.-H., Ng, Shi-Chung, Simmer, Robert L., Giranda, Vincent L.

Journal:

Year:

2001

Language:

english

File:

PDF, 780 KB

english, 2001

31

Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth

Chen, Jun, Wu, Wei, Tahir, Stephen K., Kroeger, Paul E., Rosenberg, Saul H., Cowsert, Lex M., Bennett, Frank, Krajewski, Stanislaw, Krajewska, Maryla, Welsh, Kate, Reed, John C., Ng, Shi-Chung

Journal:

Year:

2000

Language:

english

File:

PDF, 600 KB

english, 2000

32

Cloning of human GAP 43: Growth association and ischemic resurgence

Ng, Shi-Chung, de la Monte, Suzanne M., Conboy, Gary L., Karns, Larry R., Fishman, Mark C.

Journal:

Year:

1988

Language:

english

File:

PDF, 706 KB

english, 1988

33

Analysis of Temperature-Sensitive Mutations in the Simian Virus 40 Gene Encoding Virion Protein 1

Marla Behm, Henry Lowman, Shi-Chung Ng and Minou Bina

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 982 KB

english, 1988

34

Second-Generation Peptidomimetic Inhibitors of Protein Farnesyltransferase Demonstrating Improved Cellular Potency and Significant in Vivo Efficacy

O'Connor, Stephen J., Barr, Kenneth J., Wang, Le, Sorensen, Bryan K., Tasker, Andrew S., Sham, Hing, Ng, Shi-Chung, Cohen, Jerome, Devine, Edward, Cherian, Sajeev, Saeed, Badr, Zhang, Haichao, Lee, Ja

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 130 KB

english, 1999

35

Discovery of a Series of Cyclohexylethylamine-Containing Protein Farnesyltransferase Inhibitors Exhibiting Potent Cellular Activity

Henry,, Kenneth J., Wasicak, James, Tasker, Andrew S., Cohen, Jerome, Ewing, Patricia, Mitten, Michael, Larsen, John J., Kalvin, Douglas M., Swenson, Rolf, Ng, Shi-Chung, Saeed, Badr, Cherian, Sajeev,

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 222 KB

english, 1999

36

Simian Virus 40 Chromatin Interaction with the Capsid Proteins

Bina, Minou, Ng, Shi-Chung, Blasquez, Veronica

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

1983

Language:

english

File:

PDF, 2.95 MB

english, 1983

37

Synergistic effect of paclitaxel and 4-hydroxytamoxifen on estrogen receptor-negative colon cancer and lung cancer cell lines

Gu, Wen-Zhen, Chen, Zehan, Tahir, Stephen K, Rosenberg, Saul H, Ng, Shi-Chung

Journal:

Anti-Cancer Drugs

Year:

1999

File:

PDF, 445 KB

1999

38

Characterization of the anti-apoptotic mechanism of Bcl-B

ZHAI, Dayong, KE, Ning, ZHANG, Haichao, LADROR, Uri, JOSEPH, Mary, EICHINGER, Andreas, GODZIK, Adam, NG, Shi-Chung, REED, John C.

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 221 KB

english, 2003

39

Survivin does not inhibit caspase-3 activity

Banks, Damon P., Plescia, Janet, Altieri, Dario C., Chen, Jun, Rosenberg, Saul H., Zhang, Haichao, Ng, Shi-Chung

Journal:

Year:

2000

File:

PDF, 100 KB

2000